National Beer Day: Prohibition Ended 85 Years Ago SaturdayNational Beer Day: Prohibition Ended 85 Years Ago SaturdaySaturday will mark the 85th anniversary of the end of prohibition in the United States. The 21st Amendment, which repealed the 18th Amendment, took effect at 12:01 a.m. on April 7th, 1933. Jim MauriceJim Maurice